Thio Phosphoramidites
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite
Quick view. A protected adenosine building block bearing N6-benzoyl, 5'-O-DMTr, and 2'-O-TBDMS groups with a 3'-S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite functionality. CAS 1374755-65-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite is classified as thio phosphoramidites (Formula C57H65N6O8PS2Si; molecular weight 1085.36).
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite — Identity-defined 2'-O-TBDMS-rA(Bz)-3'-PS phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-adenosine-3'-PS phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O-TBDMS-rA(Bz)-3'-PS phosphoramidite
- 5'-DMT-2'-O-TBDMS-A(Bz)-3'-PS phosphoramidite
- 2'-OTBS A(Bz) thiophosphoramidite
Useful catalog search terms
- CAS 1374755-65-3
Physicochemical data
| InChIKey | ALJIYXCITZABFP-WOMFGPHHSA-N |
|---|---|
| Nucleoside | Adenosine |
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 2' protection | TBDMS |
| 3' functionality | S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite |
| PubChem CID | 102308172 |
| InChI | InChI=1S/C57H65N6O8PS2Si/c1-56(2,3)75(6,7)71-50-49(70-72(62-33-17-18-34-62)74-36-35-73-55(65)41-21-13-9-14-22-41)47(69-54(50)63-39-60-48-51(58-38-59-52(48)63)61-53(64)40-19-11-8-12-20-40)37-68-57(42-23-15-10-16-24-42,43-25-29-45(66-4)30-26-43)44-27-31-46(67-5)32-28-44/h8-16,19-32,38-39,47,49-50,54H,17-18,33-37H2,1-7H3,(H,58,59,61,64)/t47-,49-,50-,54-,72?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(SCCSC(=O)c2ccccc2)N2CCCC2)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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