Cap Analogs
m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium
Quick view. A no-CAS UNA-modified trinucleotide cap analog in triammonium form for mRNA-synthesis research. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium is classified as cap analogs.
m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium — Modified trinucleotide cap analog for mRNA-synthesis research.
For m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- CAP 4 m7G(UNA)(5')ppp(5')(2'OMeA)pG Ammonium Salt
- CAP 4 m7G(UNA)(5')ppp(5')(2'OMeA)pG
- CAP 4
Physicochemical data
| Inner-salt formula | C32H45N15O24P4 |
|---|---|
| Inner-salt molecular weight | 1147.69 |
| Counterion form | Triammonium |
| Nucleotide shorthand | m7G(UNA)(5')ppp(5')(2'-OMeA)pG |
| Cap modification | Unlocked m7G cap moiety |
| First transcribed nucleotide | 2'-O-methyladenosine |
| Triammonium molecular formula | C32H54N18O24P4 |
| Formula basis | Triammonium form |
| Triammonium molecular weight | 1198.77 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
- Cap analog selection can influence capping efficiency, orientation and downstream translation-related performance.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
- Capping outcome depends on polymerase system, cap-to-NTP ratio, transcript design and purification method.
These points describe m7G(UNA)(5')ppp(5')(2'-OMeA)pG triammonium or its named chemical feature. Broader product-family guidance is maintained on the category page.
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OR-CA-0005CAP 6 m7G(LNA)(5')ppp(5')(2'OMeA)pG Triammonium Salt
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OR-CA-0007CAP 9 m7G(2'F)(5')ppp(5')(2'OMeA)pG Ammonium Salt
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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