Halogenated Nucleosides
Trifluridine
Quick view. Trifluridine is 5-trifluoromethyl-2'-deoxyuridine, an organofluorine pyrimidine nucleoside analogue for nucleoside-metabolism and DNA-incorporation research. CAS 70-00-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Trifluridine is classified as organofluorine pyrimidine 2'-deoxyribonucleoside (Formula C10H11F3N2O5; molecular weight 296.20).
A reported mechanistic study examined trifluridine transport, thymidine-kinase phosphorylation, nucleotide handling and incorporation into DNA.
For Trifluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5-Trifluoromethyl-2'-deoxyuridine
- Trifluorothymidine
- TFT
- FTD
- 2'-5-CF3-dU
Useful catalog search terms
- CAS 70-00-8
- PubChem CID 6256
Physicochemical data
| PubChem CID | 6256 |
|---|---|
| InChIKey | VSQQQLOSPVPRAZ-RRKCRQDMSA-N |
| Modification | Trifluoromethyl group at uracil C5 |
| InChI | InChI=1S/C10H11F3N2O5/c11-10(12,13)4-2-15(9(19)14-8(4)18)7-1-5(17)6(3-16)20-7/h2,5-7,16-17H,1,3H2,(H,14,18,19)/t5-,6+,7+/m0/s1 |
| SMILES | C1[C@@H]([C@H](O[C@H]1N2C=C(C(=O)NC2=O)C(F)(F)F)CO)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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