Amino-modified Nucleosides
2-Amino-2'-deoxy-N6,N6-dimethyladenosine
Quick view. A 2'-deoxy purine nucleoside bearing 2-amino and 6-(dimethylamino) base substitutions, identified by CAS 83061-20-5. CAS 83061-20-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Amino-2'-deoxy-N6,N6-dimethyladenosine is classified as amino-modified nucleosides (Formula C12H18N6O3; molecular weight 294.31).
2-Amino-2'-deoxy-N6,N6-dimethyladenosine provides a reactive functional group for conjugation, immobilization or linker-extension studies.
For 2-Amino-2'-deoxy-N6,N6-dimethyladenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- 6-Dimethylamino-2'-deoxyguanosine
- 2'-Deoxy-6-dimethylaminoguanosine
- Adenosine, 2-amino-2'-deoxy-N,N-dimethyl-
Useful catalog search terms
- CAS 83061-20-5
- PubChem CID 134150
Physicochemical data
| PubChem CID | 134150 |
|---|---|
| InChIKey | BDQPWZYLQPUTEJ-XLPZGREQSA-N |
| Nucleoside | 2'-deoxy purine nucleoside |
| Base substitution | 2-amino; 6-(dimethylamino) |
| Sugar modification | 2'-deoxy |
| Hydroxyl state | free 3' and 5' hydroxyls |
| InChI | InChI=1S/C12H18N6O3/c1-17(2)10-9-11(16-12(13)15-10)18(5-14-9)8-3-6(20)7(4-19)21-8/h5-8,19-20H,3-4H2,1-2H3,(H2,13,15,16)/t6-,7+,8+/m0/s1 |
| SMILES | CN(C)C1=NC(=NC2=C1N=CN2[C@H]3C[C@@H]([C@H](O3)CO)O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 2-Amino-2'-deoxy-N6,N6-dimethyladenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Amino-modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.