Thio Phosphoramidites
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite
Quick view. A protected 2'-deoxyadenosine building block bearing N6-benzoyl and 5'-O-DMTr groups with a 3'-S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite functionality. CAS 178272-29-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite is classified as thio phosphoramidites (Formula C51H51N6O7PS2; molecular weight 955.10).
N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite — Identity-defined dA(Bz)-3'-PS phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-2'-deoxyadenosine-3'-PS phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- dA(Bz)-3'-PS phosphoramidite
- 5'-DMT-dA(Bz)-3'-PS phosphoramidite
- dA(Bz) thiophosphoramidite
Useful catalog search terms
- CAS 178272-29-2
Physicochemical data
| InChIKey | MLBWDUKKOAPDAN-OBBNISDBSA-N |
|---|---|
| Nucleoside | 2'-Deoxyadenosine |
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 3' functionality | S-(2-benzoylmercaptoethyl) pyrrolidino thiophosphoramidite |
| InChI | InChI=1S/C51H51N6O7PS2/c1-60-41-24-20-39(21-25-41)51(38-18-10-5-11-19-38,40-22-26-42(61-2)27-23-40)62-33-44-43(64-65(56-28-12-13-29-56)67-31-30-66-50(59)37-16-8-4-9-17-37)32-45(63-44)57-35-54-46-47(52-34-53-48(46)57)55-49(58)36-14-6-3-7-15-36/h3-11,14-27,34-35,43-45H,12-13,28-33H2,1-2H3,(H,52,53,55,58)/t43-,44+,45+,65?/m0/s1 |
| SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9 |
| Canonical SMILES | COC1=CC=C(C=C1)C(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)OC[C@@H]4[C@H](C[C@@H](O4)N5C=NC6=C(N=CN=C65)NC(=O)C7=CC=CC=C7)OP(N8CCCC8)SCCSC(=O)C9=CC=CC=C9 |
| PubChem CID | 10533897 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Thio Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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