RNA (2'-O-TBDMS) Phosphoramidites
5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite
Quick view. A protected inosine phosphoramidite bearing 5'-O-DMTr and 2'-O-TBDMS groups for research-use RNA synthesis. CAS 261518-12-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite is classified as rna (2'-o-tbdms) phosphoramidites (Formula C46H61N6O8PSi; molecular weight 885.07).
5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite — Protected inosine building block for research-use RNA synthesis.
For 5'-O-DMTr-2'-O-TBDMS-inosine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2'-O-TBDMS-rI Phosphoramidite
- 5'-DMT-2'-O-TBDMS-Inosine-3'-CE Phosphoramidite
Useful catalog search terms
- 261518-12-1
Physicochemical data
| PubChem CID | 135483567 |
|---|---|
| Nucleoside | Inosine |
| 5' protection | DMTr |
| 2' protection | TBDMS |
| 3'-O group | 2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | ZUFMOUFQBYZIHB-JFOZTMRSSA-N |
| InChI | InChI=1S/C46H61N6O8PSi/c1-31(2)52(32(3)4)61(57-27-15-26-47)59-40-38(58-44(41(40)60-62(10,11)45(5,6)7)51-30-50-39-42(51)48-29-49-43(39)53)28-56-46(33-16-13-12-14-17-33,34-18-22-36(54-8)23-19-34)35-20-24-37(55-9)25-21-35/h12-14,16-25,29-32,38,40-41,44H,15,27-28H2,1-11H3,(H,48,49,53)/t38-,40-,41-,44-,61?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(=O)[nH]cnc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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