Modified Nucleotides
2'-OMe-CTP Sodium Salt
Quick view. A sodium salt of cytidine 5'-triphosphate bearing a 2'-O-methyl substituent and an unprotected 3'-hydroxyl group. The listed CAS refers to the free-acid identity. CAS 143028-98-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
2'-OMe-CTP Sodium Salt is classified as modified nucleotides.
2'-OMe-CTP Sodium Salt supports modified RNA/antisense designs where methylated ribose positions are used to improve stability or reduce unwanted immune stimulation.
For 2'-OMe-CTP Sodium Salt, excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
Names and search terms
Confirmed or normalized name variants
- 2'-O-Methyl-CTP Sodium Salt
- 2'-O-Methylcytidine 5'-triphosphate Sodium Salt
- 2'OMe-CTP.Na
Useful catalog search terms
- 143028-98-2
Physicochemical data
| Free-acid molecular formula | C10H18N3O14P3 |
|---|---|
| Free-acid molecular weight | 497.18 |
| CAS basis | Free-acid identity |
| Salt form | Sodium salt |
| Counterion stoichiometry | Not specified |
| Sugar modification | 2'-O-methyl |
| Hydroxyl state | 3' hydroxyl unprotected |
| Phosphate state | 5'-triphosphate |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-methyl groups are widely used to increase nuclease resistance and modulate hybridization behavior.
Method limitations
- Excessive or poorly positioned substitution can reduce desired enzyme interactions or activity in some assay formats.
These points describe 2'-OMe-CTP Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: N/A
OR-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
OR-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
OR-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
OR-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
OR-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.