Modified Nucleotides
3'-O-Methylguanosine 5'-triphosphate, Tris salt
Quick view. The Tris salt form of a guanosine 5'-triphosphate bearing a methyl substituent on the ribose 3'-oxygen. CAS N/A. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
3'-O-Methylguanosine 5'-triphosphate, Tris salt is classified as 3'-o-methyl guanosine 5'-triphosphate.
3'-O-Methylguanosine 5'-triphosphate, Tris salt can be evaluated in terminally blocked nucleotide, cap-chemistry and analytical-reference workflows where 3′-O-methylation changes extension or end-group reactivity.
For 3'-O-Methylguanosine 5'-triphosphate, Tris salt, form: Tris salt.
Names and search terms
Confirmed or normalized name variants
- 3'-OMe GTP
- 3'-Methoxy-guanosine 5'-triphosphate, Tris salt
Useful catalog search terms
- 61556-45-4 free acid
Physicochemical data
| Molecular formula (free acid) | C11H18N5O14P3 |
|---|---|
| Molecular weight (free acid) | 537.21 g/mol |
| Free-acid reference CAS | 61556-45-4 |
| Form | Tris salt |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 3′-O-methylation provides a defined blocked ribose terminus and is analytically distinguishable from the corresponding 2′-O-methyl isomer.
Method limitations
- The 3′-O-methyl group blocks normal 3′-hydroxyl extension; confirm that this behavior matches the intended enzyme or synthesis workflow.
These points describe 3'-O-Methylguanosine 5'-triphosphate, Tris salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
3'-OMe-GDP Disodium Salt
Modified Nucleotides · CAS: N/A
OR-INTE-00143'-OMe-GMP
Modified Nucleotides · CAS: 400806-41-9
OR-INTE-00153'-OMe-GMP TEA Salt
Modified Nucleotides · CAS: 860605-85-2
OR-INTE-0021Im-3'-OMe-GMP
Modified Nucleotides · CAS: 1005791-93-4
OR-INTE-0023Im-GDP
Modified Nucleotides · CAS: 1199264-75-9
OR-MN-0025(-)-Emtricitabine Triphosphate Tetrasodium Salt
Modified Nucleotides · CAS: 1188407-46-6
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.