DMTr-protected Nucleosides
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac)
Quick view. N6-acetyl-protected adenosine bearing a 5'-O-DMTr group, a 2'-O-(2-cyanoethoxymethyl) substituent and a free 3'-hydroxyl. CAS 863408-41-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac) is classified as dmtr-protected nucleosides (Formula C37H38N6O8; molecular weight 694.75 g/mol).
5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac) is supplied for research use within the DMTr-protected Nucleosides product family.
For 5'-O-DMTr-2'-O-(2-cyanoethoxymethyl)-rA(Ac), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-2'-O-(2-cyanoethoxymethyl)-rA(Ac)
- 6-N-acetyl-5'-O-(4,4'-dimethoxytrityl)-2'-O-(2-cyanoethoxymethyl)adenosine
Useful catalog search terms
- CAS 863408-41-7
Physicochemical data
| Nucleoside | adenosine |
|---|---|
| Base protection | N6-acetyl |
| Hydroxyl protection | 5'-O-DMTr |
| 2' substituent | 2'-O-(2-cyanoethoxymethyl) |
| Hydroxyl state | 3' hydroxyl group unprotected |
| Calculated molecular weight | 694.75 g/mol |
| SMILES | CC(=O)NC1=C2C(=NC=N1)N(C=N2)[C@H]3[C@@H]([C@@H]([C@H](O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCOCCC#N |
| Connectivity SMILES | CC(=O)NC1=C2C(=NC=N1)N(C=N2)C3C(C(C(O3)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O)OCOCCC#N |
| InChI | InChI=1S/C37H38N6O8/c1-24(44)42-34-31-35(40-21-39-34)43(22-41-31)36-33(49-23-48-19-7-18-38)32(45)30(51-36)20-50-37(25-8-5-4-6-9-25,26-10-14-28(46-2)15-11-26)27-12-16-29(47-3)17-13-27/h4-6,8-17,21-22,30,32-33,36,45H,7,19-20,23H2,1-3H3,(H,39,40,42,44)/t30-,32-,33-,36-/m1/s1 |
| InChIKey | IQUBNLVPESSAFU-QGGAYTEESA-N |
| IUPAC name | N-[9-[(2R,3R,4R,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-3-(2-cyanoethoxymethoxy)-4-hydroxyoxolan-2-yl]purin-6-yl]acetamide |
| PubChem CID | 86630724 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DMTr-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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