Amino-modified Nucleosides
8-Amino-2'-deoxyadenosine
Quick view. An adenine-derived 2'-deoxynucleoside bearing amino substitution at purine C8, CAS 13389-09-8. CAS 13389-09-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
8-Amino-2'-deoxyadenosine is classified as amino-modified nucleosides (Formula C10H14N6O3; molecular weight 266.26).
8-Amino-2'-deoxyadenosine — Modified nucleoside for research on oligonucleotide synthesis and base-pairing.
For 8-Amino-2'-deoxyadenosine, functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
Names and search terms
Confirmed or normalized name variants
- Adenosine, 8-amino-2'-deoxy-
Useful catalog search terms
- CAS 13389-09-8
- Wikidata Q82903087
- PMID 10198432
- PMCID PMC148412
- DOI 10.1093/nar/27.9.1991
Physicochemical data
| Nucleobase scaffold | Adenine-derived purine |
|---|---|
| Amino position | C8 amino substitution |
| Sugar class | 2'-deoxyribosyl nucleoside |
| InChI | InChI=1S/C10H14N6O3/c11-8-7-9(14-3-13-8)16(10(12)15-7)6-1-4(18)5(2-17)19-6/h3-6,17-18H,1-2H2,(H2,12,15)(H2,11,13,14) |
| InChIKey | KHQCCEUMCUSZKM-UHFFFAOYSA-N |
| SMILES | N=c1[nH]c2c(N)ncnc2n1C1CC(O)C(CO)O1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe 8-Amino-2'-deoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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