GalNAc
Lipig
Quick view. Lipig is an acetyl-protected triantennary GalNAc carboxylic-acid intermediate for research-use conjugation chemistry. CAS 1332358-27-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Lipig is classified as acetyl-protected triantennary galnac glycoconjugate (Formula C78H125N7O42; molecular weight 1832.80).
Lipig — Acetyl-protected triantennary GalNAc carboxylic-acid intermediate for research-use conjugation chemistry.
For Lipig, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Useful catalog search terms
- HR-01001017
- 1332358-27-6
- C78H125N7O42
- triantennary GalNAc intermediate
- GalNAc
Physicochemical data
| Branching | Three protected GalNAc arms on a lysine-based scaffold |
|---|---|
| Reactive terminus | Carboxylic acid |
| PubChem CID | 58409185 |
| InChI | InChI=1S/C78H125N7O42/c1-45(86)81-65-71(122-54(10)95)68(119-51(7)92)59(39-116-48(4)89)125-76(65)113-36-33-107-24-21-104-27-30-110-42-62(98)79-19-15-13-17-57(84-64(100)44-112-32-29-106-23-26-109-35-38-115-78-67(83-47(3)88)73(124-56(12)97)70(121-53(9)94)61(127-78)41-118-50(6)91)74(101)85-58(75(102)103)18-14-16-20-80-63(99)43-111-31-28-105-22-25-108-34-37-114-77-66(82-46(2)87)72(123-55(11)96)69(120-52(8)93)60(126-77)40-117-49(5)90/h57-61,65-73,76-78H,13-44H2,1-12H3,(H,79,98)(H,80,99)(H,81,86)(H,82,87)(H,83,88)(H,84,100)(H,85,101)(H,102,103)/t57-,58-,59+,60+,61+,65+,66+,67+,68-,69-,70-,71+,72+,73+,76+,77+,78+/m0/s1 |
| InChIKey | RNUIVLALNYHRTI-OIZVDVEISA-N |
| SMILES | CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCCOCCOCCOCC(=O)NCCCC[C@@H](C(=O)N[C@@H](CCCCNC(=O)COCCOCCOCCO[C@H]2[C@@H]([C@H]([C@H]([C@H](O2)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C)C(=O)O)NC(=O)COCCOCCOCCO[C@H]3[C@@H]([C@H]([C@H]([C@H](O3)COC(=O)C)OC(=O)C)OC(=O)C)NC(=O)C)COC(=O)C)OC(=O)C)OC(=O)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Lipig or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the GalNAc product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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