DNA Phosphoramidites
5'-O-DMTr-N6-methyl-2'-deoxyadenosine-3'-CE phosphoramidite
Quick view. A protected N6-methyl-2'-deoxyadenosine phosphoramidite bearing a 5'-DMTr group and a 3'-cyanoethyl N,N-diisopropylphosphoramidite group. CAS 105931-58-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-N6-methyl-2'-deoxyadenosine-3'-CE phosphoramidite is classified as dna phosphoramidites (Formula C41H50N7O6P; molecular weight 767.90).
5'-O-DMTr-N6-methyl-2'-deoxyadenosine-3'-CE phosphoramidite — Identity-defined N6-methyl-dA CE phosphoramidite for research workflows involving incorporation of N6-methyl-2'-deoxyadenosine residues into synthetic oligonucleotides.
For 5'-O-DMTr-N6-methyl-2'-deoxyadenosine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N6-Me-dA phosphoramidite
- N6-methyl-dA phosphoramidite
- N6-methyl-dA CEP
- 5'-O-DMT-N6-methyl-2'-deoxyadenosine 3'-CE phosphoramidite
Useful catalog search terms
- CAS 105931-58-6
Physicochemical data
| Nucleoside | N6-Methyl-2'-deoxyadenosine |
|---|---|
| Sugar configuration | 2'-Deoxyribose |
| 5' protection | DMTr |
| 3'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| Base modification | N6-Methyl |
| PubChem CID | 86280297 |
| InChI | InChI=1S/C41H50N7O6P/c1-28(2)48(29(3)4)55(52-23-11-22-42)54-35-24-37(47-27-46-38-39(43-5)44-26-45-40(38)47)53-36(35)25-51-41(30-12-9-8-10-13-30,31-14-18-33(49-6)19-15-31)32-16-20-34(50-7)21-17-32/h8-10,12-21,26-29,35-37H,11,23-25H2,1-7H3,(H,43,44,45)/t35-,36+,37+,55?/m0/s1 |
| InChIKey | PTWRBAYAPDVZGR-JNTXQERPSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=NC6=C(N=CN=C65)NC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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