GalNAc
Peracetylated GalNAc PEG Linker-Acid-1
Quick view. Peracetylated GalNAc PEG Linker-Acid-1 is a peracetylated beta-D-GalNAc triethylene-glycol acetic acid identified by CAS 1332358-25-4. CAS 1332358-25-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Peracetylated GalNAc PEG Linker-Acid-1 is classified as peracetylated galnac peg carboxylic acid (Formula C22H35NO14; molecular weight 537.52).
Peracetylated GalNAc PEG Linker-Acid-1 can be used when comparing GalNAc ligand/linker architecture for liver-targeted oligonucleotide conjugation research.
For Peracetylated GalNAc PEG Linker-Acid-1, in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- 2-[2-[2-[2-[[3,4,6-Tri-O-acetyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetic acid
Useful catalog search terms
- 1332358-25-4
- IIEQJMVMGJMETQ-MIUGBVLSSA-N
Physicochemical data
| Systematic name | 2-[2-[2-[2-[[3,4,6-tri-O-acetyl-2-(acetylamino)-2-deoxy-beta-D-galactopyranosyl]oxy]ethoxy]ethoxy]ethoxy]acetic acid |
|---|---|
| SMILES | CC(=O)N[C@H]1[C@H](OCCOCCOCCOCC(=O)O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O |
| InChIKey | IIEQJMVMGJMETQ-MIUGBVLSSA-N |
| Sugar configuration | beta-D-GalNAc |
| Protecting groups | 3,4,6-tri-O-acetyl; N-acetyl |
| Linker functionality | Triethylene-glycol terminal acetic acid |
| InChI | InChI=1S/C22H35NO14/c1-13(24)23-19-21(36-16(4)27)20(35-15(3)26)17(11-34-14(2)25)37-22(19)33-10-9-31-6-5-30-7-8-32-12-18(28)29/h17,19-22H,5-12H2,1-4H3,(H,23,24)(H,28,29)/t17-,19-,20+,21-,22-/m1/s1 |
| Canonical SMILES | CC(=O)N[C@H]1[C@H](OCCOCCOCCOCC(=O)O)O[C@H](COC(C)=O)[C@H](OC(C)=O)[C@@H]1OC(C)=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Peracetylated GalNAc PEG Linker-Acid-1 or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the GalNAc product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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