GalNAc
Peracetylated GalNAc Pentanoic Acid (C5 Linker)
Quick view. Peracetylated GalNAc Pentanoic Acid is a saturated peracetylated GalNAc C5 carboxylic-acid linker identified by CAS 1159408-54-4. CAS 1159408-54-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Peracetylated GalNAc Pentanoic Acid (C5 Linker) is classified as peracetylated galnac c5 carboxylic-acid linker (Formula C19H29NO11; molecular weight 447.43).
Peracetylated GalNAc Pentanoic Acid (C5 Linker) can be used when comparing GalNAc ligand/linker architecture for liver-targeted oligonucleotide conjugation research.
For Peracetylated GalNAc Pentanoic Acid (C5 Linker), in-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
Names and search terms
Confirmed or normalized name variants
- Peracetylated D-galactosamine C5 linker
- GalNAc C5 linker
- Peracetylated GalNAc Pentenoic Acid
- 5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid
Useful catalog search terms
- Peracetylated GalNAc Pentanoic Acid
- 1159408-54-4
- 127243363
- CIMKBXFSXWOMDK-IQZDNPOKSA-N
Physicochemical data
| PubChem CID | 127243363 |
|---|---|
| Systematic name | 5-(((2R,3R,4R,5R,6R)-3-acetamido-4,5-diacetoxy-6-(acetoxymethyl)tetrahydro-2H-pyran-2-yl)oxy)pentanoic acid |
| SMILES | CC(=O)N[C@@H]1[C@H]([C@H]([C@H](O[C@H]1OCCCCC(=O)O)COC(=O)C)OC(=O)C)OC(=O)C |
| InChIKey | CIMKBXFSXWOMDK-IQZDNPOKSA-N |
| Linker functionality | Saturated C5 terminal carboxylic acid |
| Protecting groups | 3,4,6-tri-O-acetyl; N-acetyl |
| InChI | InChI=1S/C19H29NO11/c1-10(21)20-16-18(30-13(4)24)17(29-12(3)23)14(9-28-11(2)22)31-19(16)27-8-6-5-7-15(25)26/h14,16-19H,5-9H2,1-4H3,(H,20,21)(H,25,26)/t14-,16-,17+,18-,19-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- A defined GalNAc intermediate helps decouple ligand-linker optimization from sequence optimization.
Method limitations
- In-vitro affinity and in-vivo delivery behavior may diverge; valency, linker length and conjugation site need empirical confirmation.
These points describe Peracetylated GalNAc Pentanoic Acid (C5 Linker) or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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