Modified Nucleosides
2',3'-Dideoxyuridine
Quick view. A uridine analogue with a saturated sugar ring lacking both the 2'- and 3'-hydroxyl groups. CAS 5983-09-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Dideoxyuridine is classified as 2',3'-dideoxy pyrimidine nucleoside (Formula C9H12N2O4; molecular weight 212.20 g/mol).
2',3'-Dideoxyuridine — Reported in synthetic studies of 2',3'-dideoxynucleosides and their protected precursors.
For 2',3'-Dideoxyuridine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- Dideoxyuridine
- ddUrd
- Uridine, 2',3'-dideoxy-
Useful catalog search terms
- 5983-09-5
- BTOTXLJHDSNXMW-POYBYMJQSA-N
Physicochemical data
| InChIKey | BTOTXLJHDSNXMW-POYBYMJQSA-N |
|---|---|
| InChI | InChI=1S/C9H12N2O4/c12-5-6-1-2-8(15-6)11-4-3-7(13)10-9(11)14/h3-4,6,8,12H,1-2,5H2,(H,10,13,14)/t6-,8+/m0/s1 |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=CC(=O)NC2=O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxyuridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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