DNA Phosphoramidites
5'-O-DMTr-2-thio-2'-deoxyuridine-3'-CE phosphoramidite
Quick view. A 5'-O-DMTr-protected 2-thio-2'-deoxyuridine 3'-CE phosphoramidite for structure-specific DNA oligonucleotide synthesis research. CAS 152753-94-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2-thio-2'-deoxyuridine-3'-CE phosphoramidite is classified as dna phosphoramidites (Formula C39H47N4O7PS; molecular weight 746.90).
5'-O-DMTr-2-thio-2'-deoxyuridine-3'-CE phosphoramidite — 2-Thio-modified DNA phosphoramidite building block for structure-specific oligonucleotide synthesis research.
For 5'-O-DMTr-2-thio-2'-deoxyuridine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- DNA 2-Thio-U amidite
- 5'-O-DMT-2-thio-2'-dU-3'-phosphoramidite
Useful catalog search terms
- CAS 152753-94-1
- PubChem CID 168448654
Physicochemical data
| PubChem CID | 168448654 |
|---|---|
| InChIKey | LFZAXLODEUQTCY-LWVNILPLSA-N |
| IUPAC name | 3-[[(2R,3S,5R)-2-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-5-(4-oxo-2-sulfanylidenepyrimidin-1-yl)oxolan-3-yl]oxy-[di(propan-2-yl)amino]phosphanyl]oxypropanenitrile |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@H]1C[C@@H](O[C@@H]1COC(C2=CC=CC=C2)(C3=CC=C(C=C3)OC)C4=CC=C(C=C4)OC)N5C=CC(=O)NC5=S |
| Protection pattern | 5'-O-DMTr; 2-thio base; 2'-deoxy; 3'-O-CE phosphoramidite |
| Fluorine | Absent |
| Phosphorus stereochemistry | Unspecified |
| InChI | InChI=1S/C39H47N4O7PS/c1-27(2)43(28(3)4)51(48-24-10-22-40)50-34-25-37(42-23-21-36(44)41-38(42)52)49-35(34)26-47-39(29-11-8-7-9-12-29,30-13-17-32(45-5)18-14-30)31-15-19-33(46-6)20-16-31/h7-9,11-21,23,27-28,34-35,37H,10,24-26H2,1-6H3,(H,41,44,52)/t34-,35+,37+,51?/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the DNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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