TIPDS-protected Nucleosides
3',5'-O-TIPDS-2'-Spirocyclopropyl-U
Quick view. 3',5'-O-TIPDS-2'-Spirocyclopropyl-U is a uridine analogue containing a 3',5'-O-TIPDS bridge and a 2'-spirocyclopropyl motif. CAS 140902-00-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-O-TIPDS-2'-Spirocyclopropyl-U is classified as tipds-protected nucleosides (Formula C23H40N2O6Si2; molecular weight 496.70).
3',5'-O-TIPDS-2'-Spirocyclopropyl-U — Protected conformationally constrained uridine intermediate for research route development.
For 3',5'-O-TIPDS-2'-Spirocyclopropyl-U, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3',5'-O-TIPDS-2'-spirocyclopropyluridine
Useful catalog search terms
- CAS 140902-00-7
Physicochemical data
| Protecting-group pattern | 3',5'-O-TIPDS bridge |
|---|---|
| Constrained motif | 2'-spirocyclopropyl |
| Encoded stereochemistry | (6aR,8R,9aS) |
| Systematic name | 1-[(6aR,8R,9aS)-2,2,4,4-tetra(propan-2-yl)spiro[6,6a,8,9a-tetrahydrofuro[3,2-f][1,3,5,2,4]trioxadisilocine-9,1'-cyclopropane]-8-yl]pyrimidine-2,4-dione |
| InChIKey | MVWHOWANWWWTAF-HMXCVIKNSA-N |
| InChI | InChI=1S/C23H40N2O6Si2/c1-14(2)32(15(3)4)28-13-18-20(30-33(31-32,16(5)6)17(7)8)23(10-11-23)21(29-18)25-12-9-19(26)24-22(25)27/h9,12,14-18,20-21H,10-11,13H2,1-8H3,(H,24,26,27)/t18-,20-,21-/m1/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H](C3(CC3)[C@@H](O2)N4C=CC(=O)NC4=O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Canonical SMILES | CC(C)[Si]1(OC[C@@H]2[C@H](C3(CC3)[C@@H](O2)N4C=CC(=O)NC4=O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-family literature
These publications provide peer-reviewed context for the TIPDS-protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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