2'-FANA Nucleosides
5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine
Quick view. 5-Bromouridine derivative with a beta-D 2'-deoxy-2'-fluoro arabinofuranosyl sugar protected as the 3',5'-bis-O-benzoyl compound. CAS 213136-12-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine is classified as 2'-fana nucleosides (Formula C23H18BrFN2O7; molecular weight 533.31 g/mol).
5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 1-(3',5'-Di-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinofuranosyl)-5-bromouracil
Useful catalog search terms
- 213136-12-0
Physicochemical data
| Base scaffold | 5-Bromouridine |
|---|---|
| Sugar configuration | beta-D-arabinofuranosyl |
| Sugar modification | 2'-deoxy-2'-fluoro |
| Protecting groups | 3',5'-bis-O-benzoyl |
| InChIKey | ZUEZUNSMNFNCLZ-AJYBTWMASA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 5-Bromo-3',5'-bis-O-benzoyl-2'-deoxy-2'-fluoro-beta-D-arabinouridine or its named chemical feature. Broader product-family guidance is maintained on the category page.
Related products
2'-FANA-dG
2'-FANA Nucleosides · CAS: 103884-98-6
OR-MN-01622'-FANA-dC
2'-FANA Nucleosides · CAS: 56632-83-8
OR-MN-01632'-FANA-dT
2'-FANA Nucleosides · CAS: 69256-17-3
OR-MN-01722'-Deoxy-2'-fluoro-beta-D-arabinouridine
2'-FANA Nucleosides · CAS: 69123-94-0
OR-2FAN-00012'-Deoxy-2'-fluoro-beta-D-arabino-2-thiouridine
2'-FANA Nucleosides · CAS: 1006872-85-0
OR-2FAN-00042-Aminopurine-9-beta-D-(2'-deoxy-2'-fluoro)arabino-riboside
2'-FANA Nucleosides · CAS: 109304-04-3
Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.