Protected Nucleosides
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyladenosine
Quick view. An adenosine derivative bearing 5'-O-(4,4'-dimethoxytrityl) and 3'-O-tert-butyldimethylsilyl protecting groups, identified by CAS 81794-12-9. CAS 81794-12-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyladenosine is classified as protected nucleosides (Formula C37H45N5O6Si; molecular weight 683.90).
5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyladenosine is associated with adenine-containing building blocks or substrates for A-position incorporation and analytical comparison.
For 5'-O-(4,4'-Dimethoxytrityl)-3'-O-tert-butyldimethylsilyladenosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMTr-3'-O-TBDMS-adenosine
Useful catalog search terms
- CAS 81794-12-9
- PubChem CID 13989626
Physicochemical data
| PubChem CID | 13989626 |
|---|---|
| InChIKey | CBAUNERZXFKXOR-QSYCCZFCSA-N |
| Nucleoside | adenosine |
| Sugar protection | 5'-O-DMTr; 3'-O-TBDMS |
| Hydroxyl state | free 2' hydroxyl |
| InChI | InChI=1S/C37H45N5O6Si/c1-36(2,3)49(6,7)48-32-29(47-35(31(32)43)42-23-41-30-33(38)39-22-40-34(30)42)21-46-37(24-11-9-8-10-12-24,25-13-17-27(44-4)18-14-25)26-15-19-28(45-5)20-16-26/h8-20,22-23,29,31-32,35,43H,21H2,1-7H3,(H2,38,39,40)/t29-,31-,32-,35-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@H](O[C@H]([C@@H]1O)N2C=NC3=C(N=CN=C32)N)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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