Protected Nucleosides
5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine
Quick view. A protected guanosine intermediate bearing 5'-O-DMT, 2'-O-TBDMS and N2-dimethylformamidine groups, CAS 126922-61-0. CAS 126922-61-0. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine is classified as protected nucleosides (Formula C40H50N6O7Si; molecular weight 754.96).
5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine — A supplier aggregate describes this protected guanosine as an intermediate for RNA oligonucleotide synthesis.
For 5'-O-DMT-2'-O-TBDMS-N2-dimethylformamidine-guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 5'-O-DMT-2'-O-TBDMS-G(DMF)
- 2'-O-TBDMS-N2-DMF-5'-O-DMT-guanosine
Useful catalog search terms
- CAS 126922-61-0
- QLIITSYHYKRUSO-SPBWOXKUSA-N
- PubChem CID 136380617
Physicochemical data
| Registry name | Guanosine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-N-[(dimethylamino)methylene]-2'-O-[(1,1-dimethylethyl)dimethylsilyl]- |
|---|---|
| Protecting groups | 5'-O-DMT; 2'-O-TBDMS; N2-dimethylformamidine |
| 3' position | Free hydroxyl; not a phosphoramidite |
| PubChem CID | 136380617 |
| InChIKey | QLIITSYHYKRUSO-SPBWOXKUSA-N |
| InChI | InChI=1S/C40H50N6O7Si/c1-39(2,3)54(8,9)53-34-33(47)31(52-37(34)46-25-41-32-35(46)43-38(44-36(32)48)42-24-45(4)5)23-51-40(26-13-11-10-12-14-26,27-15-19-29(49-6)20-16-27)28-17-21-30(50-7)22-18-28/h10-22,24-25,31,33-34,37,47H,23H2,1-9H3,(H,43,44,48)/t31-,33-,34-,37-/m1/s1 |
| SMILES | CC(C)(C)[Si](C)(C)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C2N=C(NC3=O)N=CN(C)C)COC(C4=CC=CC=C4)(C5=CC=C(C=C5)OC)C6=CC=C(C=C6)OC)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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