Halogenated Nucleosides
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine
Quick view. A 3'-deoxy-3'-fluoro, 6-phenyl purine nucleoside building block for structure-specific nucleoside and oligonucleotide synthesis research. CAS 1612191-91-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine is classified as halogenated nucleosides (Formula C16H15FN4O3; molecular weight 330.31).
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine — Fluorinated, phenyl-substituted purine nucleoside building block for structure-specific nucleoside and oligonucleotide synthesis research.
For 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- (2R,3S,4S,5R)-4-Fluoro-5-(hydroxymethyl)-2-(6-phenylpurin-9-yl)oxolan-3-ol
Useful catalog search terms
- CAS 1612191-91-9
- PubChem CID 77844504
Physicochemical data
| PubChem CID | 77844504 |
|---|---|
| InChIKey | HITTYNDMWCMUFB-MMYVAXCBSA-N |
| IUPAC name | (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-(6-phenylpurin-9-yl)oxolan-3-ol |
| SMILES | C1=CC=C(C=C1)C2=C3C(=NC=N2)N(C=N3)[C@H]4[C@@H]([C@@H]([C@H](O4)CO)F)O |
| Sugar modification | 3'-deoxy-3'-fluoro |
| Purine substitution | 6-phenyl |
| InChI | InChI=1S/C16H15FN4O3/c17-11-10(6-22)24-16(14(11)23)21-8-20-13-12(18-7-19-15(13)21)9-4-2-1-3-5-9/h1-5,7-8,10-11,14,16,22-23H,6H2/t10-,11-,14-,16-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-phenylpurine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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