Phosphorus Reagents
Bis(diisopropylamino)chlorophosphine
Quick view. A chlorobis(diisopropylamino)phosphine reagent supplied for nucleic-acid phosphorylation research. CAS 56183-63-2. Catalog target purity: 97.0-103.0% assay by titration. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
Bis(diisopropylamino)chlorophosphine is classified as phosphorus reagents (Formula C12H28ClN2P; molecular weight 266.79).
Bis(diisopropylamino)chlorophosphine — Phosphorylating reagent for nucleic-acid synthesis research
For Bis(diisopropylamino)chlorophosphine, form: White to light-brown powder or crystalline solid.
Names and search terms
Confirmed or normalized name variants
- Chlorobis(N,N-diisopropylamino)phosphine
- Tetraisopropylphosphorodiamidous chloride
Useful catalog search terms
- 56183-63-2
- nucleic acid phosphorylation reagent
Physicochemical data
| IUPAC name | N-[chloro-[di(propan-2-yl)amino]phosphanyl]-N-propan-2-ylpropan-2-amine |
|---|---|
| InChIKey | FEHUTHGOLLQBNW-UHFFFAOYSA-N |
| SMILES | CC(C)N(C(C)C)P(N(C(C)C)C(C)C)Cl |
| Form | White to light-brown powder or crystalline solid |
| Storage temperature | 2-10 C |
| Melting Point | 100-110 C |
| Composition note | May contain varying amounts of diisopropylamine hydrochloride |
| PubChem CID | 2733425 |
| InChI | InChI=1S/C12H28ClN2P/c1-9(2)14(10(3)4)16(13)15(11(5)6)12(7)8/h9-12H,1-8H3 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Supplier-described protection of nucleoside 3'-hydroxyl groups
Product-specific evaluation notes
Potential advantages
- Reactive handles make the product adaptable across dye-labeling, surface-coupling and ligand-conjugation workflows.
Method limitations
- Functional handles may require orthogonal protection, pH control and rapid purification to avoid hydrolysis, oxidation or cross-reaction.
These points describe Bis(diisopropylamino)chlorophosphine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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