RNA (2'-O-TBDMS) Phosphoramidites
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite
Quick view. DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite is an N2-isobutyryl- and 2'-O-TBDMS-protected guanosine building block for research-use RNA oligonucleotide synthesis. CAS 147201-04-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite is classified as protected riboguanosine phosphoramidite (Formula C50H68N7O9PSi; molecular weight 970.20).
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite — N2-isobutyryl- and 2'-O-TBDMS-protected guanosine phosphoramidite building block for research-use RNA oligonucleotide synthesis.
For DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- iBu-rG Phosphoramidite
- DMT-2'-O-TBDMS-rG(iBu)-3'-CE-Phosphoramidite
- 2'-O-TBDMS-rG(iBu) Phosphoramidite
Useful catalog search terms
- 147201-04-5
- PubChem 135587729
- C50H68N7O9PSi
- Areterna PA009
- RNA (2'-O-TBDMS) Phosphoramidites
Physicochemical data
| Base protection | N2-isobutyryl |
|---|---|
| Ribose protection | 2'-O-TBDMS |
| Synthesis format | 5'-DMTr and 3'-2-cyanoethyl N,N-diisopropyl phosphoramidite |
| InChIKey | PGJKESPHANLWME-FTZVBZPOSA-N |
| InChI | InChI=1S/C50H68N7O9PSi/c1-32(2)45(58)54-48-53-44-41(46(59)55-48)52-31-56(44)47-43(66-68(12,13)49(7,8)9)42(65-67(63-29-17-28-51)57(33(3)4)34(5)6)40(64-47)30-62-50(35-18-15-14-16-19-35,36-20-24-38(60-10)25-21-36)37-22-26-39(61-11)27-23-37/h14-16,18-27,31-34,40,42-43,47H,17,29-30H2,1-13H3,(H2,53,54,55,58,59)/t40-,42-,43-,47-,67?/m1/s1 |
| SMILES | COc1ccc(C(OC[C@H]2O[C@@H](n3cnc4c(O)nc(NC(=O)C(C)C)nc43)[C@H](O[Si](C)(C)C(C)(C)C)[C@@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the RNA (2'-O-TBDMS) Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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