L-RNA Phosphoramidites
5'-O-DMTr-2'-O-TBDMS-beta-L-uridine-3'-CE phosphoramidite
Quick view. A beta-L-uridine building block bearing 5'-O-DMTr and 2'-O-TBDMS protection with a 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 144490-31-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
5'-O-DMTr-2'-O-TBDMS-beta-L-uridine-3'-CE phosphoramidite is classified as l-rna phosphoramidites (Formula C45H61N4O9PSi; molecular weight 861.06).
5'-O-DMTr-2'-O-TBDMS-beta-L-uridine-3'-CE phosphoramidite — Identity-defined L-rU phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For 5'-O-DMTr-2'-O-TBDMS-beta-L-uridine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- L-rU phosphoramidite
- 5'-O-DMTr-2'-O-TBDMS-L-U-3'-CE phosphoramidite
- L-RNA 2'-O-TBS U amidite
Useful catalog search terms
- CAS 144490-31-3
Physicochemical data
| InChIKey | SKNLXHRBXYGJOC-BKOBKXGTSA-N |
|---|---|
| Nucleoside | beta-L-Uridine |
| Ribofuranosyl stereochemistry | (2S,3S,4S,5S) |
| Base protection | None |
| 5' protection | DMTr |
| 2' protection | TBDMS |
| 3'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| PubChem CID | 101037436 |
| InChI | InChI=1S/C45H61N4O9PSi/c1-31(2)49(32(3)4)59(55-29-15-27-46)57-40-38(56-42(48-28-26-39(50)47-43(48)51)41(40)58-60(10,11)44(5,6)7)30-54-45(33-16-13-12-14-17-33,34-18-22-36(52-8)23-19-34)35-20-24-37(53-9)25-21-35/h12-14,16-26,28,31-32,38,40-42H,15,29-30H2,1-11H3,(H,47,50,51)/t38-,40-,41-,42-,59?/m0/s1 |
| SMILES | COc1ccc(C(OC[C@@H]2O[C@H](n3ccc(=O)[nH]c3=O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-beta-L-cytidine-3'-CE phosphoramidite
L-RNA Phosphoramidites · CAS: 237060-94-5
OR-LRP-0001N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-beta-L-adenosine-3'-CE phosphoramidite
L-RNA Phosphoramidites · CAS: 1803193-36-3
OR-LRP-0003N2-Isobutyryl-5'-O-DMTr-2'-O-TBDMS-beta-L-guanosine-3'-CE phosphoramidite
L-RNA Phosphoramidites · CAS: 679809-76-8
Product-family literature
These publications provide peer-reviewed context for the L-RNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.