Protected Nucleosides
N2-Isobutyryl-3',5'-O-TIPDS-guanosine
Quick view. A protected guanosine intermediate bearing N2-isobutyryl and cyclic 3',5'-O-TIPDS groups, identified by CAS 87865-78-9. CAS 87865-78-9. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
Request a quote Review request checklist
Product profile
N2-Isobutyryl-3',5'-O-TIPDS-guanosine is classified as protected nucleosides (Formula C26H45N5O7Si2; molecular weight 595.84).
N2-Isobutyryl-3',5'-O-TIPDS-guanosine is associated with guanine-containing building blocks or substrates for G-position incorporation and analytical comparison.
For N2-Isobutyryl-3',5'-O-TIPDS-guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- N2-Isobutyryl-3',5'-O-(tetraisopropyldisiloxane-1,3-diyl)guanosine
- 3',5'-O-TIPDS-N2-isobutyrylguanosine
- NIBu-3',5'-TIPDS-G
Useful catalog search terms
- CAS 87865-78-9
- MFCD09910466
Physicochemical data
| Nucleoside | guanosine |
|---|---|
| Base protection | N2-isobutyryl |
| Sugar protection | 3',5'-O-TIPDS |
| Free hydroxyl | 2'-OH |
| PubChem CID | 135507703 |
| InChI | InChI=1S/C26H45N5O7Si2/c1-13(2)23(33)29-26-28-22-19(24(34)30-26)27-12-31(22)25-20(32)21-18(36-25)11-35-39(14(3)4,15(5)6)38-40(37-21,16(7)8)17(9)10/h12-18,20-21,25,32H,11H2,1-10H3,(H2,28,29,30,33,34)/t18-,20-,21-,25-/m1/s1 |
| InChIKey | RYRMXMSXLHPLAT-GUQHISFFSA-N |
| SMILES | CC(C)C(=O)NC1=NC2=C(C(=O)N1)N=CN2[C@H]3[C@@H]([C@H]4[C@H](O3)CO[Si](O[Si](O4)(C(C)C)C(C)C)(C(C)C)C(C)C)O |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
2'-O-TBDMS-rG(iBu)
Protected Nucleosides · CAS: 182007-86-9
OR-PN-00435'-O-DMTr-2'-O-TBDMS-rC(Ac)
Protected Nucleosides · CAS: 121058-85-3
OR-PN-00575'-O-TBDMS-3'-O-TBDMS-5-(hydroxymethyl)-dC
Protected Nucleosides · CAS: 1257247-39-4
OR-PN-00585'-O-TBDMS-3'-O-TBDMS-5-I-dC
Protected Nucleosides · CAS: 478843-96-8
OR-PN-00673'-O-TBDMS-2'-F-dG(iBu)
Protected Nucleosides · CAS: 2382967-92-0
OR-PN-00683'-O-TBDMS-2'-F-dA(Bz)
Protected Nucleosides · CAS: 1244763-25-4
Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
Request a quote Review request checklist
Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.