Protected Nucleosides
N6-Benzoyl-2',3'-dideoxyadenosine
Quick view. A stereodefined 2',3'-dideoxyadenosine derivative protected at adenine N6 with benzoyl, identified by CAS 77244-86-1. CAS 77244-86-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Benzoyl-2',3'-dideoxyadenosine is classified as protected nucleosides (Formula C17H17N5O3; molecular weight 339.30).
N6-Benzoyl-2',3'-dideoxyadenosine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For N6-Benzoyl-2',3'-dideoxyadenosine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- N6-Benzoyl-ddA
Useful catalog search terms
- CAS 77244-86-1
- PubChem CID 485101
Physicochemical data
| Base protection | N6-benzoyl |
|---|---|
| Sugar modification | 2',3'-dideoxy; 5'-OH unprotected |
| InChIKey | ZNZDAJZEPSQWJN-QWHCGFSZSA-N |
| PubChem CID | 485101 |
| InChI | InChI=1S/C17H17N5O3/c23-8-12-6-7-13(25-12)22-10-20-14-15(18-9-19-16(14)22)21-17(24)11-4-2-1-3-5-11/h1-5,9-10,12-13,23H,6-8H2,(H,18,19,21,24)/t12-,13+/m0/s1 |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe N6-Benzoyl-2',3'-dideoxyadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Protected Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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