Modified Nucleotides
4'-Fluorouridine 5'-Triphosphate Sodium Salt
Quick view. A sodium salt of uridine 5'-triphosphate bearing fluorine at the 4' carbon while retaining free 2'- and 3'-hydroxyl groups. Counterion stoichiometry is not specified. CAS 1251838-93-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Identifier context
These notes preserve the current catalog identifiers while making their review boundary explicit.
The listed InChIKey is retained as an identity reference and does not by itself establish the salt or counterion form named on this page. Confirm the exact supplied form with OROGO.
Product profile
4'-Fluorouridine 5'-Triphosphate Sodium Salt is classified as modified nucleotides.
4'-Fluorouridine 5'-Triphosphate Sodium Salt is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 4'-Fluorouridine 5'-Triphosphate Sodium Salt, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 4'-F-UTP Sodium Salt
- 4'-Fluorouridine 5'-O-Triphosphate Sodium Salt
Useful catalog search terms
- CAS 1251838-93-3
- PubChem CID 90233147
Physicochemical data
| Parent formula | C9H14FN2O15P3 |
|---|---|
| Parent molecular weight | 502.13 |
| PubChem CID | 90233147 |
| InChIKey | JICLDCHIWOEHQY-JVZYCSMKSA-N |
| Salt form | Sodium salt |
| Counterion stoichiometry | Not specified |
| Nucleobase | Uracil |
| Sugar modification | 4'-fluoro |
| Hydroxyl state | 2' and 3' hydroxyl groups free |
| Phosphate state | 5'-triphosphate |
| InChIKey review status | The listed InChIKey is retained as an identity reference and does not by itself establish the salt or counterion form named on this page. Confirm the exact supplied form with OROGO. |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 4'-Fluorouridine 5'-Triphosphate Sodium Salt or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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