L-RNA Phosphoramidites
N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-beta-L-cytidine-3'-CE phosphoramidite
Quick view. A protected beta-L-cytidine building block bearing N4-acetyl, 5'-O-DMTr, and 2'-O-TBDMS groups with a 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 237060-94-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-beta-L-cytidine-3'-CE phosphoramidite is classified as l-rna phosphoramidites (Formula C47H64N5O9PSi; molecular weight 902.11).
N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-beta-L-cytidine-3'-CE phosphoramidite — Identity-defined L-rC(Ac) phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N4-Acetyl-5'-O-DMTr-2'-O-TBDMS-beta-L-cytidine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- L-rC(Ac) phosphoramidite
- DMT-2'-O-TBDMS-L-rC(Ac) phosphoramidite
- 5'-O-DMTr-2'-O-TBDMS-N4-acetyl-L-cytidine-3'-CE phosphoramidite
- OR-LRP-0002
Useful catalog search terms
- CAS 237060-94-5
Physicochemical data
| InChIKey | QKWKXYVKGFKODW-ZYRNLWDWSA-N |
|---|---|
| Nucleoside | Beta-L-cytidine |
| Base protection | N4-Acetyl |
| 5' protection | DMTr |
| 2' protection | TBDMS |
| 3'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| PubChem CID | 70700204 |
| InChI | InChI=1S/C47H64N5O9PSi/c1-32(2)52(33(3)4)62(58-30-16-28-48)60-42-40(59-44(43(42)61-63(11,12)46(6,7)8)51-29-27-41(49-34(5)53)50-45(51)54)31-57-47(35-17-14-13-15-18-35,36-19-23-38(55-9)24-20-36)37-21-25-39(56-10)26-22-37/h13-15,17-27,29,32-33,40,42-44H,16,30-31H2,1-12H3,(H,49,50,53,54)/t40-,42-,43-,44-,62?/m0/s1 |
| SMILES | COc1ccc(C(OC[C@@H]2O[C@H](n3ccc(NC(C)=O)nc3=O)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the L-RNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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