L-RNA Phosphoramidites
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-beta-L-adenosine-3'-CE phosphoramidite
Quick view. A beta-L-adenosine building block bearing N6-benzoyl, 5'-O-DMTr, and 2'-O-TBDMS protection with a 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1803193-36-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-beta-L-adenosine-3'-CE phosphoramidite is classified as l-rna phosphoramidites (Formula C53H66N7O8PSi; molecular weight 988.21).
N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-beta-L-adenosine-3'-CE phosphoramidite — Identity-defined L-rA(Bz) phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-2'-O-TBDMS-beta-L-adenosine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- L-rA(Bz) phosphoramidite
- 5'-O-DMTr-2'-O-TBDMS-L-A(Bz)-3'-CE phosphoramidite
- DMT-2'-O-TBDMS-L-rA(Bz) phosphoramidite
Useful catalog search terms
- CAS 1803193-36-3
Physicochemical data
| InChIKey | FFXHNCNNHASXCT-XMSTWNTJSA-N |
|---|---|
| Nucleoside | beta-L-Adenosine |
| Ribofuranosyl stereochemistry | (2S,3S,4S,5S) |
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 2' protection | TBDMS |
| 3'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| PubChem CID | 13872239 |
| InChI | InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-46-44(33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41)66-51(47(46)68-70(10,11)52(5,6)7)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m0/s1 |
| SMILES | COc1ccc(C(OC[C@@H]2O[C@H](n3cnc4c(NC(=O)c5ccccc5)ncnc43)[C@@H](O[Si](C)(C)C(C)(C)C)[C@H]2OP(OCCC#N)N(C(C)C)C(C)C)(c2ccccc2)c2ccc(OC)cc2)cc1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the L-RNA Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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