UNA Phosphoramidites
N4-Acetyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-cytidine-3'-CE phosphoramidite
Quick view. A fully protected C-UNA building block comprising N4-acetyl-2',3'-seco-cytidine with 5'-O-DMTr, 2'-O-benzoyl, and 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1120329-56-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N4-Acetyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-cytidine-3'-CE phosphoramidite is classified as una phosphoramidites (Formula C48H56N5O10P; molecular weight 893.96).
N4-Acetyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-cytidine-3'-CE phosphoramidite — Identity-defined UNA-C phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N4-Acetyl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-cytidine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- UNA-C(Ac)-CE phosphoramidite
- Ac-C-UNA-CE phosphoramidite
- UNA-C(N-Ac) phosphoramidite
Useful catalog search terms
- CAS 1120329-56-7
Physicochemical data
| Nucleobase | Cytosine |
|---|---|
| Backbone | 2',3'-seco-cytidine (UNA-C) |
| Base protection | N4-Acetyl |
| Hydroxyl protection | 5'-O-DMTr and 2'-O-benzoyl |
| Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| PubChem CID | 138376033 |
| InChI | InChI=1S/C48H56N5O10P/c1-34(2)53(35(3)4)64(61-30-14-28-49)62-32-43(63-45(33-59-46(55)37-15-10-8-11-16-37)52-29-27-44(50-36(5)54)51-47(52)56)31-60-48(38-17-12-9-13-18-38,39-19-23-41(57-6)24-20-39)40-21-25-42(58-7)26-22-40/h8-13,15-27,29,34-35,43,45H,14,30-33H2,1-7H3,(H,50,51,54,56)/t43-,45-,64?/m1/s1 |
| InChIKey | UMUWXRLDMCRCFS-GXOVKUNTSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)OC[C@@H](COC(C1=CC=CC=C1)(C2=CC=C(C=C2)OC)C3=CC=C(C=C3)OC)O[C@H](COC(=O)C4=CC=CC=C4)N5C=CC(=NC5=O)NC(=O)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
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OR-UP-00045'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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