UNA Phosphoramidites
5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite
Quick view. A fully protected U-UNA building block comprising 2',3'-seco-uridine with 5'-O-DMTr, 2'-O-benzoyl, and 3'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 1120329-48-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite is classified as una phosphoramidites (Formula C46H53N4O10P; molecular weight 852.92).
5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite — Identity-defined UNA-U phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For 5'-O-DMTr-2'-O-benzoyl-2',3'-seco-uridine-3'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- UNA-U-CE phosphoramidite
- U-UNA-CE phosphoramidite
- 5'-DMTr-2'-Bz-3'-O-CEP-UNA-U
Useful catalog search terms
- CAS 1120329-48-7
Physicochemical data
| InChIKey | MHRGEJFLFYZLJI-LZOZAVILSA-N |
|---|---|
| Nucleobase | Uracil |
| Backbone | 2',3'-seco-uridine (UNA-U) |
| Hydroxyl protection | 5'-O-DMTr and 2'-O-benzoyl |
| Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| InChI | InChI=1S/C46H53N4O10P/c1-33(2)50(34(3)4)61(58-29-13-27-47)59-31-41(60-43(49-28-26-42(51)48-45(49)53)32-56-44(52)35-14-9-7-10-15-35)30-57-46(36-16-11-8-12-17-36,37-18-22-39(54-5)23-19-37)38-20-24-40(55-6)25-21-38/h7-12,14-26,28,33-34,41,43H,13,29-32H2,1-6H3,(H,48,51,53)/t41-,43-,61?/m1/s1 |
| SMILES | C(C1=CC=CC=C1)(=O)OC[C@H](N1C(NC(C=C1)=O)=O)O[C@H](COC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)COP(N(C(C)C)C(C)C)OCCC#N |
| Canonical SMILES | C(C1=CC=CC=C1)(=O)OC[C@H](N1C(NC(C=C1)=O)=O)O[C@H](COC(C1=CC=CC=C1)(C1=CC=C(C=C1)OC)C1=CC=C(C=C1)OC)COP(N(C(C)C)C(C)C)OCCC#N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
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OR-UP-0003N2-Isobutyryl-5'-O-DMTr-2'-O-benzoyl-2',3'-seco-guanosine-3'-CE phosphoramidite
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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