2'-FANA Nucleosides
2'-Deoxy-2'-fluoroarabinoadenosine
Quick view. A 2'-FANA adenosine building block for structure-specific modified-nucleoside, nucleotide and oligonucleotide synthesis research. CAS 20227-41-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2'-Deoxy-2'-fluoroarabinoadenosine is classified as 2'-fana nucleosides (Formula C10H12FN5O3; molecular weight 269.23).
2'-Deoxy-2'-fluoroarabinoadenosine — 2'-FANA adenosine building block for structure-specific modified-nucleoside, nucleotide and oligonucleotide synthesis research.
For 2'-Deoxy-2'-fluoroarabinoadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 2'-FANA-A
- 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine
- 6-Aminopurine-2'-fluoro-2'-deoxyarabinofuranoside
- TNU0085
- ND09204
- BUP06688
Useful catalog search terms
- CAS 20227-41-2
Physicochemical data
| Systematic identity | 9-(2-Deoxy-2-fluoro-beta-D-arabinofuranosyl)adenine |
|---|---|
| InChIKey | ZGYYPTJWJBEXBC-GQTRHBFLSA-N |
| SMILES | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CO)[C@@H](O)[C@@H]1F |
| Sugar modification | 2'-deoxy-2'-fluoro-beta-D-arabino |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2'-Deoxy-2'-fluoroarabinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.