3'-O-TBDMS Phosphoramidites
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite
Quick view. A protected adenosine building block bearing N6-benzoyl, 5'-O-DMTr, and 3'-O-TBDMS groups with a 2'-cyanoethyl N,N-diisopropylphosphoramidite functionality. CAS 129451-75-8. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite is classified as 3'-o-tbdms phosphoramidites (Formula C53H66N7O8PSi; molecular weight 988.19).
N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite — Identity-defined 3'-O-TBDMS adenosine 2'-phosphoramidite for research workflows involving solid-phase oligonucleotide synthesis.
For N6-Benzoyl-5'-O-DMTr-3'-O-TBDMS-adenosine-2'-CE phosphoramidite, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3'-O-TBDMS-rA(Bz) phosphoramidite
- 3'-TBDMS-Bz-rA phosphoramidite
- DMT-3'-O-TBDMS-A(Bz)-2'-CE phosphoramidite
Useful catalog search terms
- CAS 129451-75-8
Physicochemical data
| Nucleoside | Adenosine |
|---|---|
| Base protection | N6-Benzoyl |
| 5' protection | DMTr |
| 3' protection | TBDMS |
| 2'-Coupling group | 2-Cyanoethyl N,N-diisopropylphosphoramidite |
| MDL number | MFCD00274109 |
| PubChem CID | 14376009 |
| InChI | InChI=1S/C53H66N7O8PSi/c1-36(2)60(37(3)4)69(65-32-18-31-54)67-47-46(68-70(10,11)52(5,6)7)44(66-51(47)59-35-57-45-48(55-34-56-49(45)59)58-50(61)38-19-14-12-15-20-38)33-64-53(39-21-16-13-17-22-39,40-23-27-42(62-8)28-24-40)41-25-29-43(63-9)30-26-41/h12-17,19-30,34-37,44,46-47,51H,18,32-33H2,1-11H3,(H,55,56,58,61)/t44-,46-,47-,51-,69?/m1/s1 |
| InChIKey | HRYAQLIYKSXPET-RFMFGJHUSA-N |
| SMILES | CC(C)N(C(C)C)P(OCCC#N)O[C@@H]1[C@@H]([C@H](O[C@H]1N2C=NC3=C(N=CN=C32)NC(=O)C4=CC=CC=C4)COC(C5=CC=CC=C5)(C6=CC=C(C=C6)OC)C7=CC=C(C=C7)OC)O[Si](C)(C)C(C)(C)C |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Related products
Product-family literature
These publications provide peer-reviewed context for the 3'-O-TBDMS Phosphoramidites product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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