OROGO PRODUCT CATEGORY
Sulfurizing Reagents
Quick view. Reagents used to introduce phosphorothioate linkages during solid-phase oligonucleotide synthesis and process-development studies. This category currently includes 7 products. Sulfur-transfer reagents are evaluated in place of an oxidation step when preparing phosphorothioate-containing oligonucleotides for research.
Category guide
Sulfur-transfer reagents are evaluated in place of an oxidation step when preparing phosphorothioate-containing oligonucleotides for research.
Compare reagent concentration, solvent compatibility, sulfurization time, preparation stability, conversion and byproduct profile.
Confirm identity and assay, control water and reagent age, then qualify conversion on representative sequences before routine use.
Product-family considerations
- Fits established phosphoramidite-cycle workflows with appropriate method validation.
- Provides a practical route to phosphorothioate-containing sequences without redesigning the full synthesis strategy.
- Sulfurization time, reagent concentration, solvent quality and instrument compatibility can strongly affect conversion and impurity profile.
- Some sulfurizing reagents have stability, odor, dissolution behavior or byproduct considerations, so fresh method qualification is recommended.
Category literature
These publications provide background for the Sulfurizing Reagents product family. Individual product pages only show additional product- or feature-relevant references.
Selection checklist
| Exact identity | Match the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable. |
|---|---|
| Specification | Define target purity, analytical method, water or residual-solvent concerns and any application-specific acceptance limits. |
| Workflow fit | Share the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility. |
| Supply need | Provide initial quantity, expected future scale, packaging preference, timeline and documentation requirements. |
Product comparison
This snapshot compares up to eight products in the current catalog order. It uses published catalog fields only; confirm the exact form, pack size, specification and current availability by inquiry.
Swipe or scroll horizontally to compare all fields.
| Product name | OR catalog no. | CAS | Purity / specification | Supply status |
|---|---|---|---|---|
| 3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH) | OR-SR-0006 | 178318-21-3 | By inquiry | Inquiry only |
| DDTT Sulfurizing Reagent | OR-SR-0001 | 1192027-04-5 | By inquiry | Inquiry only |
| Bis(phenylacetyl) Disulfide (PADS) | OR-SR-0002 | 15088-78-5 | By inquiry | Inquiry only |
| Beaucage Reagent | OR-SR-0003 | 66304-01-6 | By inquiry | Inquiry only |
| Xanthane Hydride (ADTT) | OR-SR-0004 | 6846-35-1 | By inquiry | Inquiry only |
| Tetraethylthiuram Disulfide (TETD) | OR-SR-0005 | 97-77-8 | By inquiry | Inquiry only |
| Dimethylthiuram Disulfide (DTD) | OR-SR-0007 | 2438-90-6 | By inquiry | Inquiry only |
7 products
3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH)By inquiry · CAS: 178318-21-3
OR-SR-0006
DDTT Sulfurizing ReagentBy inquiry · CAS: 1192027-04-5
OR-SR-0001
Bis(phenylacetyl) Disulfide (PADS)By inquiry · CAS: 15088-78-5
OR-SR-0002
Beaucage ReagentBy inquiry · CAS: 66304-01-6
OR-SR-0003
Xanthane Hydride (ADTT)By inquiry · CAS: 6846-35-1
OR-SR-0004
Tetraethylthiuram Disulfide (TETD)By inquiry · CAS: 97-77-8
OR-SR-0005
Dimethylthiuram Disulfide (DTD)By inquiry · CAS: 2438-90-6
OR-SR-0007Frequently asked questions
What are typical uses for Sulfurizing Reagents?
Sulfur-transfer reagents are evaluated in place of an oxidation step when preparing phosphorothioate-containing oligonucleotides for research.
What should be confirmed before ordering Sulfurizing Reagents?
Compare reagent concentration, solvent compatibility, sulfurization time, preparation stability, conversion and byproduct profile.
Are custom quantities or related analogs available?
OROGO reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.
Need help selecting a product?
Tell our scientists about your target chemistry, workflow, required purity and scale. We can help identify a catalog product, related analog or custom route.