Sulfurizing Reagents
3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH)
Quick view. EDITH is a sulfur-transfer reagent used in phosphorothioate oligonucleotide synthesis workflows. CAS 178318-21-3. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH) is classified as sulfurizing reagents (Formula C4H5NO2S2; molecular weight 163.22).
3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH) — Sulfur transfer in phosphorothioate oligonucleotide synthesis workflows.
For 3-Ethoxy-1,2,4-dithiazoline-5-one (EDITH), confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- EDITH
- 3-Ethoxy-1,2,4-dithiazolidine-5-one
- 5-Ethoxy-3H-1,2,4-dithiazol-3-one
Useful catalog search terms
- 3-Ethoxy-1,2,4-dithiazoline-5-one
- CAS 178318-21-3
Physicochemical data
| SMILES | CCOC1=NC(=O)SS1 |
|---|---|
| InChI | InChI=1S/C4H5NO2S2/c1-2-7-4-5-3(6)8-9-4/h2H2,1H3 |
| Reagent class | Oligonucleotide sulfur-transfer reagent |
| PubChem CID | 10986576 |
| InChIKey | RZIJZXUDFRSADE-UHFFFAOYSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-relevant literature
The publications below discuss named chemistry or a structural feature represented by this product. They provide scientific context only and are not an OROGO lot specification or product-performance claim.
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Technology platforms
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