Modified Nucleosides
2',3'-Dideoxycytidine
Quick view. A stereodefined cytidine analog lacking the 2'- and 3'-hydroxy groups, identified by CAS 7481-89-2. CAS 7481-89-2. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2',3'-Dideoxycytidine is classified as modified nucleosides (Formula C9H13N3O3; molecular weight 211.22).
2',3'-Dideoxycytidine can be evaluated in chain-termination, sequencing-control or polymerase-specific substrate studies.
For 2',3'-Dideoxycytidine, polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
Names and search terms
Confirmed or normalized name variants
- ddC
- Zalcitabine
Useful catalog search terms
- CAS 7481-89-2
- PubChem CID 24066
Physicochemical data
| Sugar modification | 2',3'-dideoxy |
|---|---|
| Abbreviation | ddC |
| InChIKey | WREGKURFCTUGRC-POYBYMJQSA-N |
| PubChem CID | 24066 |
| InChI | InChI=1S/C9H13N3O3/c10-7-3-4-12(9(14)11-7)8-2-1-6(5-13)15-8/h3-4,6,8,13H,1-2,5H2,(H2,10,11,14)/t6-,8+/m0/s1 |
| SMILES | C1C[C@@H](O[C@@H]1CO)N2C=CC(=NC2=O)N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- Dideoxy analogs provide clear extension-stop behavior when accepted by a polymerase.
Method limitations
- Polymerase acceptance varies; absence of a 3′-OH prevents further extension after incorporation.
These points describe 2',3'-Dideoxycytidine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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