2'-FANA Nucleosides
2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine
Quick view. 2'-Fluoro-beta-D-arabino nucleoside bearing 2-chloro and N6-cyclopentyl substitution on the purine base. CAS 2216764-33-7. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is classified as 2'-fana nucleosides (Formula C15H19ClFN5O3; molecular weight 371.80 g/mol).
2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 2216764-33-7
Physicochemical data
| Sugar configuration | 2'-deoxy-2'-fluoro-beta-D-arabino |
|---|---|
| Base substitution | 2-chloro; N6-cyclopentyl |
| InChIKey | KPEIGDNTXVZUQD-SZRLZVLASA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 2-Chloro-N6-cyclopentyl-2'-deoxy-2'-fluoro-beta-D-arabinoadenosine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Feature and workflow background
These publications discuss a broader chemistry feature or workflow identified from the catalog name or product family. They are background reading only, not evidence for the exact OROGO product, supplied form, lot specification, availability or performance.
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Technology platforms
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