Modified Nucleosides
2'-O,4'-C-[(S)-Ethylidene]-5-methyluridine
Quick view. A constrained-ethyl 5-methyluridine nucleoside with the reviewed (S)-cEt bicyclic sugar configuration. CAS 1197032-96-4. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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![Chemical structure of 2'-O,4'-C-[(S)-Ethylidene]-5-methyluridine](/structures/75c295257fc799f8.svg)
Product profile
2'-O,4'-C-[(S)-Ethylidene]-5-methyluridine is classified as modified nucleosides (Formula C12H16N2O6; molecular weight 284.27).
2'-O,4'-C-[(S)-Ethylidene]-5-methyluridine is associated with cytosine-containing building blocks or substrates for C-position incorporation and analytical comparison.
For 2'-O,4'-C-[(S)-Ethylidene]-5-methyluridine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 2',4'-Constrained ethyl 5-methyluridine
- (S)-cEt-5-Me-rU
- 1-[2,5-Anhydro-6-deoxy-4-(hydroxymethyl)-alpha-L-mannofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
Useful catalog search terms
- CAS 1197032-96-4
Physicochemical data
| InChIKey | LVNFLHPRWWSZDA-XCUBXJTOSA-N |
|---|---|
| SMILES | C[C@H]1[C@]2([C@H]([C@@H](O1)[C@@H](O2)N3C=C(C(=O)NC3=O)C)O)CO |
| Sugar modification | 2'-O,4'-C-(S)-ethylidene constrained bicyclic sugar |
| Nucleobase | 5-Methyluracil |
| InChI | InChI=1S/C12H16N2O6/c1-5-3-14(11(18)13-9(5)17)10-7-8(16)12(4-15,20-10)6(2)19-7/h3,6-8,10,15-16H,4H2,1-2H3,(H,13,17,18)/t6-,7+,8-,10+,12-/m0/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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