Modified Nucleosides
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine
Quick view. A stereodefined guanosine derivative bearing cyclic 3',5'-O-TIPDS protection and a free 2'-hydroxyl, CAS 69304-44-5. CAS 69304-44-5. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine is classified as modified nucleosides (Formula C22H39N5O6Si2; molecular weight 525.70 g/mol).
3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine — Cyclic 3',5'-O-TIPDS-protected guanosine building block for modified nucleoside chemistry.
For 3',5'-O-(1,1,3,3-Tetraisopropyl-1,3-disiloxanediyl)guanosine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 3',5'-O-TIPPS-guanosine
- 3',5'-O-[Tetrakis(1-methylethyl)-1,3-disiloxanediyl]-guanosine
Useful catalog search terms
- 69304-44-5
- PubChem CID 136662828
- CWVNMKRKFJYCCC-QTQZEZTPSA-N
Physicochemical data
| PubChem CID | 136662828 |
|---|---|
| IUPAC name | 9-[(6aR,8R,9R,9aS)-9-hydroxy-2,2,4,4-tetra(propan-2-yl)-6a,8,9,9a-tetrahydro-6H-furo[3,2-f][1,3,5,2,4]trioxadisilocin-8-yl]-2-amino-1H-purin-6-one |
| InChIKey | CWVNMKRKFJYCCC-QTQZEZTPSA-N |
| InChI | InChI=1S/C22H39N5O6Si2/c1-11(2)34(12(3)4)30-9-15-18(32-35(33-34,13(5)6)14(7)8)17(28)21(31-15)27-10-24-16-19(27)25-22(23)26-20(16)29/h10-15,17-18,21,28H,9H2,1-8H3,(H3,23,25,26,29)/t15-,17-,18-,21-/m1/s1 |
| SMILES | CC(C)[Si]1(OC[C@@H]2[C@H]([C@H]([C@@H](O2)N3C=NC4=C3N=C(NC4=O)N)O)O[Si](O1)(C(C)C)C(C)C)C(C)C |
| Stereochemistry | (6aR,8R,9R,9aS) protected ribose system |
| Protecting group | Cyclic 3',5'-O-TIPDS |
| Free hydroxyl | 2'-OH |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Additional application examples
- Reference compound for chemical identity research involving 3',5'-O-TIPDS-guanosine.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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