Modified Nucleosides
4'-Methylthymidine
Quick view. A thymidine derivative bearing an additional methyl substituent at the 4'-carbon of the 2'-deoxyribose ring, CAS 139925-84-1. CAS 139925-84-1. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
4'-Methylthymidine is classified as modified nucleosides (Formula C11H16N2O5; molecular weight 256.25).
4'-Methylthymidine is associated with thymidine-containing building blocks or substrates for DNA synthesis and analytical comparison.
For 4'-Methylthymidine, confirm the current specification, storage conditions and downstream-method compatibility before routine use.
Names and search terms
Confirmed or normalized name variants
- 4'-C-Methylthymidine
- beta-4'-Methylthymidine
- beta-4'-MeT
Useful catalog search terms
- CAS 139925-84-1
- PubChem CID 453629
Physicochemical data
| IUPAC name | 1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)-5-methyloxolan-2-yl]-5-methylpyrimidine-2,4-dione |
|---|---|
| InChI | InChI=1S/C11H16N2O5/c1-6-4-13(10(17)12-9(6)16)8-3-7(15)11(2,5-14)18-8/h4,7-8,14-15H,3,5H2,1-2H3,(H,12,16,17)/t7-,8+,11+/m0/s1 |
| InChIKey | BKEITBKYNOYEOH-VAOFZXAKSA-N |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@@](O2)(C)CO)O |
| Sugar substitution | 4'-C-Methyl |
| Nucleobase | Thymine (5-methyluracil) |
| Hydroxyl state | Free 3'- and 5'-hydroxyls |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
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Product-family literature
These publications provide peer-reviewed context for the Modified Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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