2′-MOE / Succinates
5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate
Quick view. 5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate is listed for research-use inquiry as a support-loading intermediate. Exact supplied form, specification, packaging and current availability require confirmation. CAS N/A. Catalog target purity: Specification by inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Structure confirmation
This item requires structure confirmation before quotation. Send the target structure, CAS number, SMILES, InChI or drawing for our technical review.
Canonical name plus a structure drawing, SMILES, InChI or unambiguous CAS number.
Protecting groups, stereochemistry, salt or counterion, hydration and requested form.
Agreed identity and purity criteria are documented in the quotation, specification and lot-specific data package.
Catalog status
Scope. "Available for inquiry" is not a stock claim. Operating tier is a catalog-merchandising priority. Development phase and program context are shown only where the reviewed catalog source provides a mapping; they describe the chemistry platform and do not claim that OROGO supplies the named program.
| Supply status | Available for inquiry |
|---|---|
| Operating tier | Priority |
| Development context | ↑ Upstream — reviewed as a supporting input; no direct development phase is assigned |
| CAS status | Not published for this exact form |
Product profile
5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate is classified as 2′-moe / succinates.
5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate is relevant to high-stability antisense oligonucleotide gapmer and affinity-tuning research.
For 5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate, mOE placement needs design control, especially when RNase H recruitment or steric profile matters.
Name-declared catalog attributes
These values are transcribed from the approved catalog name and taxonomy. They do not establish CAS, full molecular structure, salt form, stereochemical assignment, assay or supply specification.
| Product family | 3'-Succinate precursor |
|---|---|
| Sugar modification | 2'-MOE |
| 5'-O protecting group | DMT |
| Nucleoside notation | 5-Me-rU(T) |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-O-MOE motifs are often selected for enhanced nuclease resistance and improved duplex stability.
Method limitations
- MOE placement needs design control, especially when RNase H recruitment or steric profile matters.
These points describe 5'-DMT-2'-MOE-5-Me-rU(T) 3'-succinate or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Succinates product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
Catalog-derived platform membership for navigating related chemistry and verifiable product sets.