Halogenated Nucleosides
6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine
Quick view. Beta-D 6-methoxypurine nucleoside bearing a 3'-deoxy-3'-fluoro ribofuranosyl sugar. CAS 2072145-35-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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Product profile
6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is classified as halogenated nucleosides (Formula C11H13FN4O4; molecular weight 284.25 g/mol).
6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine is commonly assessed in siRNA, antisense and aptamer-style designs where ribose modification is used to tune stability and binding.
For 6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Useful catalog search terms
- 2072145-35-6
Physicochemical data
| Sugar substitution | 3'-deoxy-3'-fluoro beta-D-ribofuranosyl |
|---|---|
| Purine substitution | 6-methoxy |
| InChIKey | JYAVXAIZAFVSMN-HUKYDQBMSA-N |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 6-Methoxy-9-(3-deoxy-3-fluoro-beta-D-ribofuranosyl)-9H-purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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