Halogenated Nucleosides
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine
Quick view. A 3'-deoxy-3'-fluoro purine nucleoside bearing a morpholinyl-pyridyl substituent for structure-specific synthesis research. CAS 1612191-98-6. Catalog target purity: By inquiry. Availability: Inquiry only — contact OROGO to confirm current availability.
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![Chemical structure of 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine](/structures/1e6dae327116be78.svg)
Product profile
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine is classified as halogenated nucleosides (Formula C19H21FN6O4; molecular weight 416.40).
9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine — Fluorinated, morpholinyl-pyridyl-substituted purine nucleoside building block for structure-specific synthesis research.
For 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine, coupling, deprotection and biological performance remain sequence- and position-dependent.
Names and search terms
Confirmed or normalized name variants
- 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(4-morpholinyl)pyridin-3-yl]purine
Useful catalog search terms
- CAS 1612191-98-6
- PubChem CID 77844629
Physicochemical data
| PubChem CID | 77844629 |
|---|---|
| InChIKey | MJURWFUMNWGTJB-KJMSJTNLSA-N |
| IUPAC name | (2R,3S,4S,5R)-4-fluoro-5-(hydroxymethyl)-2-[6-(6-morpholin-4-yl-3-pyridinyl)purin-9-yl]oxolan-3-ol |
| SMILES | C1COCCN1C2=NC=C(C=C2)C3=C4C(=NC=N3)N(C=N4)[C@H]5[C@@H]([C@@H]([C@H](O5)CO)F)O |
| Sugar modification | 3'-deoxy-3'-fluoro |
| Purine substitution | 6-[6-(morpholin-4-yl)pyridin-3-yl] |
| InChI | InChI=1S/C19H21FN6O4/c20-14-12(8-27)30-19(17(14)28)26-10-24-16-15(22-9-23-18(16)26)11-1-2-13(21-7-11)25-3-5-29-6-4-25/h1-2,7,9-10,12,14,17,19,27-28H,3-6,8H2/t12-,14-,17-,19-/m1/s1 |
Release documentation
The current specification defines the analytical method and acceptance criteria; the released lot result is reported on the CoA.
Additional HPLC, MS or NMR documentation can be agreed during technical review where available.
Product-specific evaluation notes
Potential advantages
- 2′-fluoro motifs can improve nuclease resistance while preserving RNA-like geometry in many sequence contexts.
Method limitations
- Coupling, deprotection and biological performance remain sequence- and position-dependent.
These points describe 9-(3-Deoxy-3-fluoro-beta-D-ribofuranosyl)-6-[6-(morpholin-4-yl)pyridin-3-yl]purine or its named chemical feature. Broader product-family guidance is maintained on the category page.
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Product-family literature
These publications provide peer-reviewed context for the Halogenated Nucleosides product family and its named chemistry. They are background reading only, not evidence for the exact product, supplied form, lot specification, availability or performance.
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Technology platforms
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