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OROGO PRODUCT DIRECTORY

Natural RNA Phosphoramidites

2′-O-TBDMS-protected ribonucleoside phosphoramidites for solid-phase RNA synthesis. Confirm the exact identity, supplied form, specification, package and current availability on the product page or by inquiry.

Products4
PlatformNatural RNA
Product formPhosphoramidites
Use scopeResearch use only

Category guide

Typical use

RNA (2'-O-TBDMS) Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

How to select

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

How to qualify

Review identity, chromatographic purity, phosphorus-related quality attributes, water sensitivity and performance in a short test sequence.

Product-family considerations

Common advantages
  • Phosphoramidite chemistry is modular, automated and compatible with fast sequence iteration.
  • Modified sugar, base or linker motifs let researchers tune duplex stability, specificity, hydrophobicity, steric profile and downstream conjugation options.
Common limitations
  • Modified amidites can require adjusted coupling time, activator choice, deprotection conditions and analytical release methods.
  • Moisture sensitivity and storage history are important because degraded amidite can reduce coupling efficiency.
  • Silyl-protected RNA monomers require careful deprotection planning to protect product integrity.

Selection checklist

Exact identityMatch the canonical name with a CAS number, structure, SMILES or drawing; confirm stereochemistry, protecting groups and salt form where applicable.
SpecificationDefine target purity, analytical method, water or residual-solvent concerns and application-specific acceptance limits.
Workflow fitShare the reaction, enzyme, sequence, solvent system, support or analytical method used to evaluate compatibility.
Supply needProvide initial quantity, expected future scale, packaging preference, timeline and documentation requirements.

Product comparison

This snapshot compares up to eight products using published catalog fields only. Confirm the exact supplied form, pack size, specification and current availability by inquiry.

Swipe or scroll horizontally to compare all fields.

Product nameOR catalog no.CASPurity / specificationSupply statusChemical class
DMTr-2'-O-TBDMS-rU-3'-CE-PhosphoramiditeOR-R2OT-0022118362-03-1Specification by inquiryInquiry onlyProtected uridine phosphoramidite
DMTr-2'-O-TBDMS-rA(Bz)-3'-CE-PhosphoramiditeOR-R2OT-0023104992-55-4Specification by inquiryInquiry onlyProtected riboadenosine phosphoramidite
DMTr-2'-O-TBDMS-rG(iBu)-3'-CE-PhosphoramiditeOR-R2OT-0024147201-04-5Specification by inquiryInquiry onlyProtected riboguanosine phosphoramidite
DMTr-2'-O-TBDMS-rC(Ac)-3'-CE-PhosphoramiditeOR-R2OT-0025121058-88-6Specification by inquiryInquiry onlyProtected ribocytidine phosphoramidite

4 products

Category literature

Background literature for this product family; it does not establish an OROGO product specification, supplied form, availability or performance.

Frequently asked questions

What are typical uses for RNA (2'-O-TBDMS) Phosphoramidites?

RNA (2'-O-TBDMS) Phosphoramidites products provide protected, sequence-addressable building blocks for solid-phase oligonucleotide synthesis and modified-sequence research.

What should be confirmed before ordering RNA (2'-O-TBDMS) Phosphoramidites?

Confirm base and sugar identity, protecting groups, stereochemistry, linker or label position, and compatibility with coupling and deprotection conditions.

Are custom quantities or related analogs available?

OROGO reviews custom package sizes, catalog-adjacent analogs and research-use custom synthesis requests against the target structure, purity, scale and timeline.

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